Facilitation of the L-type calcium current in rabbit sino-atrial cells: effect on cardiac automaticity.

OBJECTIVE: The L-type Ca(2+) current (I(Ca,L)) contributes to the generation and modulation of the pacemaker action potential (AP). We investigated facilitation of I(Ca,L) in sino-atrial cells. METHODS: Facilitation was studied in regularly-beating cells isolated enzymatically from young albino rabb...

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Bibliographic Details
Main Authors: Mangoni, M, Fontanaud, P, Noble, P, Noble, D, Benkemoun, H, Nargeot, J, Richard, S
Format: Journal article
Language:English
Published: 2000