Interleukin-4 inhibits kappa light chain expression and NF kappa B activation but not I kappa B alpha degradation in 70Z/3 murine pre-B cells.

The murine pre-B cell line 70Z/3 responds to lipopolysaccharide by up-regulating the surface expression of kappa (kappa) light chain through activation of the transcription factor NF kappa B. Interleukin-4 (IL-4), a T cell cytokine, is a known inhibitor of some LPS-mediated events. We investigated w...

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Bibliographic Details
Main Authors: Clarke, C, Taylor-Fishwick, D, Hales, A, Chernajovsky, Y, Sugamura, K, Feldmann, M, Foxwell, B
Format: Journal article
Language:English
Published: 1995