A concise and efficient synthesis of (-)-allosamizoline.
A regio- and stereocontrolled total synthesis of (-)-allosamizoline is described. The key steps for this synthesis are ring-closing metathesis to form the cyclopentene core, halocyclization to afford the oxazoline ring, and finally stereoselective alkene radical addition followed by an alkene isomer...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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