Observation of the noncovalent assembly and disassembly pathways of the chaperone complex MtGimC by mass spectrometry.

We have analyzed a newly described archaeal GimC/prefoldin homologue, termed MtGimC, by using nanoflow electrospray coupled with time-of-flight MS. The molecular weight of the complex from Methanobacterium thermoautotrophicum corresponds to a well-defined hexamer of two alpha subunits and four beta...

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Bibliographic Details
Main Authors: Fändrich, M, Tito, M, Leroux, MR, Rostom, A, Hartl, F, Dobson, C, Robinson, C
Format: Journal article
Language:English
Published: 2000