Liver-stage vaccines for malaria

Liver-stage vaccines for malaria

The development of an efficacious <em>P. falciparum</em> malaria vaccine remains a top priority. Pre-erythrocytic vaccine efforts have traditionally focussed on two well- known antigens, CSP and TRAP, yet thousands of antigens are expressed throughout the liver-stage. The work described...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Longley, RJ
Awduron Eraill:	Hill, A
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2013
Pynciau:	Biology (medical sciences) Immunology Parasitology Malaria Infectious diseases

Eitemau Tebyg

Developing novel blood-stage malaria vaccines
gan: Douglas, AD
Cyhoeddwyd: (2015)

Enhancing the efficacy of viral vector blood-stage malaria vaccines
gan: Forbes, E
Cyhoeddwyd: (2011)

Pre-clinical development of viral vectored transmission-blocking malaria vaccines
gan: Kapulu, MC
Cyhoeddwyd: (2014)

Hepcidin regulation in Malaria
gan: Spottiswoode, N
Cyhoeddwyd: (2015)

Transcutaneous delivery of T Cell-inducing viral vector Malaria vaccines by microneedle patches
gan: Pearson, FE
Cyhoeddwyd: (2011)

Analysis of b cell responses to blood-stage malaria antigens in humans following immunization with candidate vaccines and controlled human malaria infection
gan: Elias, SC
Cyhoeddwyd: (2014)

Effect of hemoglobins S and C on the in vivo expression and immune recognition of Plasmodium falciparum erythrocyte membrane protein 1 variants in Malian children
gan: Beaudry, J
Cyhoeddwyd: (2012)

Assessment of novel liver-stage vaccines using transgenic rodent malaria parasites
gan: Salman, AM
Cyhoeddwyd: (2014)

Malaria pre-erythrocytic stage vaccines: targeting antigen combinations
gan: Bauza, K
Cyhoeddwyd: (2012)

Long term efficacy of a pre-erythrocytic malaria vaccine and correlates of protection in children residing in a malaria endemic country
gan: Olotu, A
Cyhoeddwyd: (2013)

Identifying genetic determinants of impaired PfEMP1 export in Plasmodium falciparum-infected erythrocytes
gan: Neal, AT
Cyhoeddwyd: (2014)

Leishmania infantum asymptomatic infection in inflammatory bowel disease patients under anti-TNF therapy
gan: M. Carmen Guillén, et al.
Cyhoeddwyd: (2020-05-01)

An analysis of non-coding RNAs in Plasmodium falciparum and their potential role in antigenic variation
gan: Christodoulou, Z
Cyhoeddwyd: (2012)

Identification and characterization of two salmon louse heme peroxidases and their potential as vaccine antigens
gan: Elisabeth Gislefoss, et al.
Cyhoeddwyd: (2023-10-01)

Towards improved blood-stage malaria vaccines: characterising the underlying immunogenicity of vaccine adjuvants and vectors
gan: de Cassan, S
Cyhoeddwyd: (2011)

CCR2 Is Dispensable for Disease Resolution but Required for the Restoration of Leukocyte Homeostasis Upon Experimental Malaria-Associated Acute Respiratory Distress Syndrome
gan: Emilie Pollenus, et al.
Cyhoeddwyd: (2021-02-01)

Corrigendum: CCR2 Is Dispensable for Disease Resolution but Required for the Restoration of Leukocyte Homeostasis Upon Experimental Malaria-Associated Acute Respiratory Distress Syndrome
gan: Emilie Pollenus, et al.
Cyhoeddwyd: (2022-06-01)

Heritability of malaria in Africa
gan: Mackinnon, M, et al.
Cyhoeddwyd: (2005)

T Helper Plasticity Is Orchestrated by STAT3, Bcl6, and Blimp-1 Balancing Pathology and Protection in Malaria
gan: Victor H. Carpio, et al.
Cyhoeddwyd: (2020-07-01)

Understanding vaccine induced protective immunity to Mycobacterium tuberculosis
gan: Ronan, E
Cyhoeddwyd: (2011)

Understanding the link between interleukin 17 and vaccine-induced protection in tuberculosis
gan: Griffiths, K
Cyhoeddwyd: (2012)

Assessment of anti-merozoite antibody function in the context of blood-stage malaria vaccine development
gan: Llewellyn, D
Cyhoeddwyd: (2014)

NK cells contribute to the resolution of experimental malaria-associated acute respiratory distress syndrome after antimalarial treatment
gan: Emilie Pollenus, et al.
Cyhoeddwyd: (2024-09-01)

Malaria elimination modelling in the context of antimalarial drug resistance
gan: Maude, R
Cyhoeddwyd: (2013)

Immunomic identification of malaria antigens associated with protection in mice
gan: Siau, Anthony, et al.
Cyhoeddwyd: (2020)

NLRP12-expressing dendritic cells mediate both dissemination of infection and adaptive immune responses in visceral leishmaniasis
gan: Diogo Garcia Valadares, et al.
Cyhoeddwyd: (2023-03-01)

Functional impact of CD161 on T cells
gan: Smith, K
Cyhoeddwyd: (2013)

Host and viral factors that determine the clinical outcome of hepatitis C virus genotype 3a infection
gan: Humphreys, I, et al.
Cyhoeddwyd: (2011)

Human genetic resistance to malaria.
gan: Williams, T
Cyhoeddwyd: (2009)

A Plasmodium falciparum ATP-binding cassette transporter is essential for liver stage entry into schizogony
gan: Debashree Goswami, et al.
Cyhoeddwyd: (2022-05-01)

The role of the cytoplasmic domain of the macrophage scavenger receptor MARCO in adhesion and uptake
gan: Kroos, M
Cyhoeddwyd: (2008)

Antigenic variation and its evolution in P. falciparum malaria
gan: Noble, RJ
Cyhoeddwyd: (2014)

Examining the relationship between genetic variation at G6PD and severe malaria
gan: Shah, SS
Cyhoeddwyd: (2011)

Variable spikes in tick-borne encephalitis incidence in 2006 independent of variable tick abundance but related to weather
gan: Randolph, S, et al.
Cyhoeddwyd: (2008)

Chemokine, cytokine and haematological profiles in Sprague-Dawley rats co-infected with Plasmodium berghei ANKA and Trichinella zimbabwensis-A laboratory animal model for malaria and tissue-dwelling nematodes co-infection
gan: Pretty Murambiwa, et al.
Cyhoeddwyd: (2020-02-01)

The different impact of drug-resistant Leishmania on the transcription programs activated in neutrophils
gan: Míriam Díaz-Varela, et al.
Cyhoeddwyd: (2024-05-01)

Leishmania amazonensis sabotages host cell SUMOylation for intracellular survival
gan: Kendi Okuda, et al.
Cyhoeddwyd: (2022-09-01)

Memory T cell responses in influenza A infection and vaccination in humans
gan: Chui, C
Cyhoeddwyd: (2012)

An age-structured model to evaluate the potential of novel malaria-control interventions: a case study of fungal biopesticide sprays
gan: Hancock, P, et al.
Cyhoeddwyd: (2009)

Host genetic factors and vaccine-induced immunity to hepatitis B virus infection
gan: Hennig, B, et al.
Cyhoeddwyd: (2008)