MBL genotype and risk of invasive pneumococcal disease: a case-control study.

BACKGROUND: Streptococcus pneumoniae is a major cause of morbidity and mortality in developed and developing countries. No common genetic determinants of susceptibility have been defined. Mannose-binding lectin (MBL) is a key mediator of innate host immunity that activates the complement pathway an...

Full description

Bibliographic Details
Main Authors: Roy, S, Knox, K, Segal, S, Griffiths, D, Moore, C, Welsh, K, Smarason, A, Day, N, McPheat, W, Crook, D, Hill, A
Format: Journal article
Language:English
Published: 2002