Effects of altering CpG dinucleotide composition in small DNA viruses

<p>CpG dinucleotides are underrepresented in mammalian genomes and in many viruses infecting them. Previous studies have shown that increasing CpG frequencies in various RNA viruses and retroviruses reduces replicative fitness but the effects of this compositional modification are unknown in D...

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Bibliographic Details
Main Author: Loew, L
Other Authors: Simmonds, P
Format: Thesis
Language:English
Published: 2020
Subjects: