Dry-coated live viral vector vaccines delivered by nanopatch microprojections retain long-term thermostability and induce transgene-specific T cell responses in mice

The disadvantages of needle-based immunisation motivate the development of simple, low cost, needle-free alternatives. Vaccine delivery to cutaneous environments rich in specialised antigen-presenting cells using microprojection patches has practical and immunological advantages over conventional ne...

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Bibliographic Details
Main Authors: Pearson, F, McNeilly, C, Crichton, M, Primiero, C, Yukiko, SR, Fernando, G, Chen, X, Gilbert, S, Hill, A, Kendall, M
Format: Journal article
Language:English
Published: Public Library of Science 2013