Mutational analysis of the PA and PB2 subunits of the influenza RNA polymerase complex leads to new insights into function
The RNA-dependent RNA polymerase complex of influenza A virus consists of three subunits, PB1, PB2 and PA. To investigate the function of the PA subunit, we mutated evolutionarily conserved amino acids to alanines in the C-terminal third of PA of influenza A/WSN/33 that shows the highest degree of c...
Egile Nagusiak: | , , , , , , |
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Formatua: | Conference item |
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2004
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