Particle size distribution of exosomes and microvesicles determined by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and resistive pulse sensing.

BACKGROUND: Enumeration of extracellular vesicles has clinical potential as a biomarker for disease. In biological samples, the smallest and largest vesicles typically differ 25-fold in size, 300,000-fold in concentration, 20,000-fold in volume, and 10,000,000-fold in scattered light. Because of thi...

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Bibliographic Details
Main Authors: van der Pol, E, Coumans, F, Grootemaat, A, Gardiner, C, Sargent, I, Harrison, P, Sturk, A, van Leeuwen, T, Nieuwland, R
Format: Journal article
Language:English
Published: 2014