Quantitative mass imaging of single biological macromolecules

The cellular processes underpinning life are orchestrated by proteins and their interactions. The associated structural and dynamic heterogeneity, despite being key to function, poses a fundamental challenge to existing analytical and structural methodologies. We used interferometric scattering micr...

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Bibliographic Details
Main Authors: Young, G, Hundt, N, Cole, D, Fineberg, A, Andrecka, J, Tyler, A, Olerinyova, A, Ansari, A, Marklund, EG, Collier, MP, Chandler, SA, Tkachenko, O, Allen, J, Crispin, M, Billington, N, Takagi, Y, Sellers, JR, Eichmann, C, Selenko, P, Frey, L, Riek, R, Galpin, MR, Struwe, WB, Benesch, JLP, Kukura, P
Format: Journal article
Published: American Association for the Advancement of Science 2018