AN ALTERNATIVE PROPOSAL FOR THE MODE OF INHIBITION OF GLYCOSIDASE ACTIVITY BY POLYHYDROXYLATED PIPERIDINES, PYRROLIDINES AND INDOLIZIDINES - IMPLICATIONS FOR THE MECHANISM OF ACTION OF SOME GLYCOSIDASES
It is proposed that polyhydroxylated alkaloids inhibit glycosidase activity by a mechanism which suggests that the enzyme-catalysed hydrolysis of some glycosides may proceed by cleavage of the endocyclic (ring) carbon-oxygen bond, rather than the exocyclic (anomeric) carbon-oxygen bond. © 1985.
| Main Author: | |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
1985
|