AN ALTERNATIVE PROPOSAL FOR THE MODE OF INHIBITION OF GLYCOSIDASE ACTIVITY BY POLYHYDROXYLATED PIPERIDINES, PYRROLIDINES AND INDOLIZIDINES - IMPLICATIONS FOR THE MECHANISM OF ACTION OF SOME GLYCOSIDASES
It is proposed that polyhydroxylated alkaloids inhibit glycosidase activity by a mechanism which suggests that the enzyme-catalysed hydrolysis of some glycosides may proceed by cleavage of the endocyclic (ring) carbon-oxygen bond, rather than the exocyclic (anomeric) carbon-oxygen bond. © 1985.
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| Format: | Journal article |
| Language: | English |
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1985
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| _version_ | 1797090354623676416 |
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| author | Fleet, G |
| author_facet | Fleet, G |
| author_sort | Fleet, G |
| collection | OXFORD |
| description | It is proposed that polyhydroxylated alkaloids inhibit glycosidase activity by a mechanism which suggests that the enzyme-catalysed hydrolysis of some glycosides may proceed by cleavage of the endocyclic (ring) carbon-oxygen bond, rather than the exocyclic (anomeric) carbon-oxygen bond. © 1985. |
| first_indexed | 2024-03-07T03:17:22Z |
| format | Journal article |
| id | oxford-uuid:b6427796-f037-4b96-9b2e-2e37405d3c82 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:17:22Z |
| publishDate | 1985 |
| record_format | dspace |
| spelling | oxford-uuid:b6427796-f037-4b96-9b2e-2e37405d3c822022-03-27T04:39:39ZAN ALTERNATIVE PROPOSAL FOR THE MODE OF INHIBITION OF GLYCOSIDASE ACTIVITY BY POLYHYDROXYLATED PIPERIDINES, PYRROLIDINES AND INDOLIZIDINES - IMPLICATIONS FOR THE MECHANISM OF ACTION OF SOME GLYCOSIDASESJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b6427796-f037-4b96-9b2e-2e37405d3c82EnglishSymplectic Elements at Oxford1985Fleet, GIt is proposed that polyhydroxylated alkaloids inhibit glycosidase activity by a mechanism which suggests that the enzyme-catalysed hydrolysis of some glycosides may proceed by cleavage of the endocyclic (ring) carbon-oxygen bond, rather than the exocyclic (anomeric) carbon-oxygen bond. © 1985. |
| spellingShingle | Fleet, G AN ALTERNATIVE PROPOSAL FOR THE MODE OF INHIBITION OF GLYCOSIDASE ACTIVITY BY POLYHYDROXYLATED PIPERIDINES, PYRROLIDINES AND INDOLIZIDINES - IMPLICATIONS FOR THE MECHANISM OF ACTION OF SOME GLYCOSIDASES |
| title | AN ALTERNATIVE PROPOSAL FOR THE MODE OF INHIBITION OF GLYCOSIDASE ACTIVITY BY POLYHYDROXYLATED PIPERIDINES, PYRROLIDINES AND INDOLIZIDINES - IMPLICATIONS FOR THE MECHANISM OF ACTION OF SOME GLYCOSIDASES |
| title_full | AN ALTERNATIVE PROPOSAL FOR THE MODE OF INHIBITION OF GLYCOSIDASE ACTIVITY BY POLYHYDROXYLATED PIPERIDINES, PYRROLIDINES AND INDOLIZIDINES - IMPLICATIONS FOR THE MECHANISM OF ACTION OF SOME GLYCOSIDASES |
| title_fullStr | AN ALTERNATIVE PROPOSAL FOR THE MODE OF INHIBITION OF GLYCOSIDASE ACTIVITY BY POLYHYDROXYLATED PIPERIDINES, PYRROLIDINES AND INDOLIZIDINES - IMPLICATIONS FOR THE MECHANISM OF ACTION OF SOME GLYCOSIDASES |
| title_full_unstemmed | AN ALTERNATIVE PROPOSAL FOR THE MODE OF INHIBITION OF GLYCOSIDASE ACTIVITY BY POLYHYDROXYLATED PIPERIDINES, PYRROLIDINES AND INDOLIZIDINES - IMPLICATIONS FOR THE MECHANISM OF ACTION OF SOME GLYCOSIDASES |
| title_short | AN ALTERNATIVE PROPOSAL FOR THE MODE OF INHIBITION OF GLYCOSIDASE ACTIVITY BY POLYHYDROXYLATED PIPERIDINES, PYRROLIDINES AND INDOLIZIDINES - IMPLICATIONS FOR THE MECHANISM OF ACTION OF SOME GLYCOSIDASES |
| title_sort | alternative proposal for the mode of inhibition of glycosidase activity by polyhydroxylated piperidines pyrrolidines and indolizidines implications for the mechanism of action of some glycosidases |
| work_keys_str_mv | AT fleetg analternativeproposalforthemodeofinhibitionofglycosidaseactivitybypolyhydroxylatedpiperidinespyrrolidinesandindolizidinesimplicationsforthemechanismofactionofsomeglycosidases AT fleetg alternativeproposalforthemodeofinhibitionofglycosidaseactivitybypolyhydroxylatedpiperidinespyrrolidinesandindolizidinesimplicationsforthemechanismofactionofsomeglycosidases |