The expression and localization of membrane type-1 matrix metalloproteinase in human abdominal aortic aneurysms.

BACKGROUND AND OBJECTIVE: Matrix metalloproteinase-2 (MMP-2) degrades both fibrillar collagens and elastin. MMP-2 is secreted as a latent 72-kd proenzyme that must be proteolytically processed to the 62-kd active form. In our laboratory we demonstrated a significant increase of active, matrix-bound...

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Bibliographic Details
Main Authors: Nollendorfs, A, Greiner, T, Nagase, H, Baxter, B
Format: Journal article
Language:English
Published: 2001