The tumour suppressor ASPP2 plays a novel role in the maintenance of epithelial cell polarity

<p>ASPP2 has been identified as a haploinsufficient tumour suppressor in mice, and an activator of the apoptotic function of the p53 family. Yeast two-hybrid experiments have also shown that ASPP2 interacts with a large number of proteins involved in other major signalling pathways. The mechan...

Full description

Bibliographic Details
Main Author: Sottocornola, R
Other Authors: Lu, X
Format: Thesis
Language:English
Published: 2010
Subjects: