The tumour suppressor ASPP2 plays a novel role in the maintenance of epithelial cell polarity
<p>ASPP2 has been identified as a haploinsufficient tumour suppressor in mice, and an activator of the apoptotic function of the p53 family. Yeast two-hybrid experiments have also shown that ASPP2 interacts with a large number of proteins involved in other major signalling pathways. The mechan...
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Format: | Thesis |
Language: | English |
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2010
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