Charge engineering reveals the roles of ionizable side chains in electrospray ionization mass spectrometry
In solution, the charge of a protein is intricately linked to its stability, but electrospray ionization distorts this connection, potentially limiting the ability of native mass spectrometry to inform about protein structure and dynamics. How the behavior of intact proteins in the gas phase depends...
| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Język: | English |
| Wydane: |
American Chemical Society
2021
|