Multiscale natural moves refine macromolecules using single-particle electron microscopy projection images.
The method presented here refines molecular conformations directly against projections of single particles measured by electron microscopy. By optimizing the orientation of the projection at the same time as the conformation, the method is well-suited to two-dimensional class averages from cryoelect...
Main Authors: | , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2012
|