Base excision repair targets for cancer therapy.

Base excision repair targets for cancer therapy.

Cellular DNA repair is a frontline system that is responsible for maintaining genome integrity and thus preventing premature aging and cancer by repairing DNA lesions and strand breaks caused by endogenous and exogenous mutagens. However, it is also the principal cellular system in cancer cells that...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας:	Dianov, G
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2011

Παρόμοια τεκμήρια

Targeting base excision repair to improve cancer therapies.
ανά: Sharma, R, κ.ά.
Έκδοση: (2007)

Monitoring base excision repair by in vitro assays.
ανά: Dianov, G
Έκδοση: (2003)

Base excision repair fidelity in normal and cancer cells.
ανά: Chan, K, κ.ά.
Έκδοση: (2006)

Mammalian base excision repair: the forgotten archangel.
ανά: Dianov, G, κ.ά.
Έκδοση: (2013)

Co-ordination of base excision repair and genome stability.
ανά: Parsons, J, κ.ά.
Έκδοση: (2013)

DNA repair fidelity of base excision repair pathways in human cell extracts.
ανά: Zhang, Q, κ.ά.
Έκδοση: (2005)

The emerging role of Mule and ARF in the regulation of base excision repair.
ανά: Khoronenkova, S, κ.ά.
Έκδοση: (2011)

The emerging role of Mule and ARF in the regulation of base excision repair
ανά: Khoronenkova, S, κ.ά.
Έκδοση: (2011)

In vitro base excision repair using mammalian cell extracts.
ανά: Parsons, J, κ.ά.
Έκδοση: (2012)

Orchestration of base excision repair by controlling the rates of enzymatic activities.
ανά: Allinson, S, κ.ά.
Έκδοση: (2004)

DNA base excision repair: the Achilles' heel of tumour cells and their microenvironment?
ανά: Poletto, M, κ.ά.
Έκδοση: (2017)

Exchangeability of mammalian DNA ligases between base excision repair pathways.
ανά: Sleeth, K, κ.ά.
Έκδοση: (2004)

Monitoring base excision repair proteins on damaged DNA using human cell extracts.
ανά: Parsons, J, κ.ά.
Έκδοση: (2004)

p53 coordinates base excision repair to prevent genomic instability
ανά: Poletto, M, κ.ά.
Έκδοση: (2016)

Targeting the 8-oxodG Base Excision Repair Pathway for Cancer Therapy
ανά: Anna Piscone, κ.ά.
Έκδοση: (2025-01-01)

Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability
ανά: Markkanen, E, κ.ά.
Έκδοση: (2015)

XRCC1-DNA polymerase beta interaction is required for efficient base excision repair.
ανά: Dianova, I, κ.ά.
Έκδοση: (2004)

CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.
ανά: Parsons, J, κ.ά.
Έκδοση: (2008)

DNA polymerase beta promotes recruitment of DNA ligase III alpha-XRCC1 to sites of base excision repair.
ανά: Parsons, J, κ.ά.
Έκδοση: (2005)

Isolation of a small molecule inhibitor of DNA base excision repair.
ανά: Madhusudan, S, κ.ά.
Έκδοση: (2005)

Overexpression of DNA polymerase beta results in an increased rate of frameshift mutations during base excision repair.
ανά: Chan, K, κ.ά.
Έκδοση: (2007)

Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.
ανά: Parsons, J, κ.ά.
Έκδοση: (2009)

Role of Base Excision Repair in Innate Immune Cells and Its Relevance for Cancer Therapy
ανά: Shengyuan Zhao, κ.ά.
Έκδοση: (2022-02-01)

Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells
ανά: Poletto, M, κ.ά.
Έκδοση: (2017)

Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients
ανά: Chen, X, κ.ά.
Έκδοση: (2018)

USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β.
ανά: Parsons, J, κ.ά.
Έκδοση: (2011)

Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.
ανά: Yang, J, κ.ά.
Έκδοση: (2010)

Regulation of the base excision repair pathway
ανά: Fletcher, S, κ.ά.
Έκδοση: (2017)

Base excision repair and the role of <it>MUTYH</it>
ανά: Kairupan Carla, κ.ά.
Έκδοση: (2007-12-01)

Exploiting Base Excision Repair to Improve Therapeutic Approaches for Pancreatic Cancer
ανά: George eSharbeen, κ.ά.
Έκδοση: (2015-03-01)

CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair.
ανά: Ström, C, κ.ά.
Έκδοση: (2011)

Bacillus Calmette-Guerin Increases Base Excision Repair in Bladder Cancer Cells
ανά: Selçuk Keskin, κ.ά.
Έκδοση: (2021-03-01)

Base Sequence Context Effects on Nucleotide Excision Repair
ανά: Yuqin Cai, κ.ά.
Έκδοση: (2010-01-01)

The Base Excision Repair Pathway in the Nematode Caenorhabditis elegans
ανά: Noha Elsakrmy, κ.ά.
Έκδοση: (2020-12-01)

Haglund Excision and Suture Bridge Repair
ανά: Albert T. Anastasio MD, κ.ά.
Έκδοση: (2023-02-01)

Functional DNA repair capacity assays : a focus on base excision repair
ανά: Chaim, Isaac Alexander
Έκδοση: (2016)

Lycopene Protects against Smoking-Induced Lung Cancer by Inducing Base Excision Repair
ανά: Junrui Cheng, κ.ά.
Έκδοση: (2020-07-01)

Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer.
ανά: Kevin J Lee, κ.ά.
Έκδοση: (2019-01-01)

DNA repair in cancer stem cells as a factor for glioma resistance to radiotherapy
ανά: Yu. S. Makusheva, κ.ά.
Έκδοση: (2015-07-01)

DNA Damage and Base Excision Repair in Mitochondria and Their Role in Aging
ανά: Ricardo Gredilla
Έκδοση: (2011-01-01)