Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid–base transporters and auto-regulate cardiomyocyte pH
<p><strong>Aims</strong></p> In cardiomyocytes, acute disturbances to intracellular pH (pHi) are promptly corrected by a system of finely tuned sarcolemmal acid–base transporters. However, these fluxes become thermodynamically re-balanced in acidic environments, which inadver...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2021
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