Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid–base transporters and auto-regulate cardiomyocyte pH
<p><strong>Aims</strong></p> In cardiomyocytes, acute disturbances to intracellular pH (pHi) are promptly corrected by a system of finely tuned sarcolemmal acid–base transporters. However, these fluxes become thermodynamically re-balanced in acidic environments, which inadver...
Main Authors: | , , , , , , , , , , , , , , |
---|---|
格式: | Journal article |
語言: | English |
出版: |
Oxford University Press
2021
|