Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid–base transporters and auto-regulate cardiomyocyte pH

Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid–base transporters and auto-regulate cardiomyocyte pH

<p><strong>Aims</strong></p> In cardiomyocytes, acute disturbances to intracellular pH (pHi) are promptly corrected by a system of finely tuned sarcolemmal acid–base transporters. However, these fluxes become thermodynamically re-balanced in acidic environments, which inadver...

書誌詳細
主要な著者:	Wilson, AD, Richards, MA, Curtis, MK, Gunadasa-Rohling, M, Monterisi, S, Loonat, AA, Miller, JJ, Ball, V, Lewis, A, Tyler, DJ, Moshnikova, A, Andreev, OA, Reshetnyak, YK, Carr, C, Swietach, P
フォーマット:	Journal article
言語:	English
出版事項:	Oxford University Press 2021

類似資料

Targeting Acidic Diseased Tissues by pH-Triggered Membrane-Associated Peptide Folding
著者:: Yana K. Reshetnyak, 等
出版事項: (2020-04-01)

Sarcolemmal localisation of Na+/H+ exchange and Na+-HCO3- co-transport influences the spatial regulation of intracellular pH in rat ventricular myocytes.
著者:: Garciarena, C, 等
出版事項: (2013)

Nitric oxide modulates cardiomyocyte pH control through a biphasic effect on sodium/hydrogen exchanger-1
著者:: Richards, M, 等
出版事項: (2019)

Cardiomyocyte Na+/H+ exchanger-1 activity is reduced in hypoxia
著者:: Kandilci, H, 等
出版事項: (2021)

Targeting acidic pre-metastatic niche in lungs by pH low insertion peptide and its utility for anti-metastatic therapy
著者:: Toma Matsui, 等
出版事項: (2023-11-01)

Increased sarcolemmal Na+/H+ exchange activity in hypertrophied myocytes from dogs with chronic atrioventricular block
著者:: Marcel evan Borren, 等
出版事項: (2013-11-01)

Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis
著者:: Nicolas Valenzuela, 等
出版事項: (2016-03-01)

Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart
著者:: Hulikova, A, 等
出版事項: (2022)

Spatial regulation of intracellular pH in multicellular strands of neonatal rat cardiomyocytes.
著者:: Swietach, P, 等
出版事項: (2010)

Gating of cardiac gap junctional channels at acid and alkaline pH
著者:: Swietach, P, 等
出版事項: (2005)

Cardiomyocyte Na+/H+ Exchanger-1 Activity Is Reduced in Hypoxia
著者:: Hilmi Burak Kandilci, 等
出版事項: (2021-01-01)

ADAM23 in Cardiomyocyte Inhibits Cardiac Hypertrophy by Targeting FAK‐AKT Signaling
著者:: Mei Xiang, 等
出版事項: (2018-09-01)

Na⁺ ions as spatial intracellular messengers for co-ordinating Ca²⁺ signals during pH heterogeneity in cardiomyocytes.
著者:: Swietach, P, 等
出版事項: (2015)

Incorporation of Omega-3 Fatty Acids Into Human Skeletal Muscle Sarcolemmal and Mitochondrial Membranes Following 12 Weeks of Fish Oil Supplementation
著者:: Christopher J. Gerling, 等
出版事項: (2019-03-01)

Phenotypic screen of sixty-eight colorectal cancer cell lines identifies CEACAM6 and CEACAM5 as markers of acid-resistance
著者:: Michl, J, 等
出版事項: (2024)

Effects of Sarcolemmal Background Ca2+ Entry and Sarcoplasmic Ca2+ Leak Currents on Electrophysiology and Ca2+ Transients in Human Ventricular Cardiomyocytes: A Computational Comparison
著者:: Molly E. Streiff, 等
出版事項: (2022-06-01)

Effective derivation of ventricular cardiomyocytes from hPSCs using ascorbic acid-containing maturation medium
著者:: Ji-eun Kim, 等
出版事項: (2023-12-01)

Acid-extrusion from tissue: the interplay between membrane transporters and pH buffers.
著者:: Hulikova, A, 等
出版事項: (2012)

A barter economy in tumors: exchanging metabolites through gap junctions
著者:: Swietach, P, 等
出版事項: (2019)

Sistem penghantaran faks : pelayan faks /
著者:: 361231 Azmin Abdul Rahim
出版事項: (1998)

A and B utrophin in human muscle and sarcolemmal A-utrophin associated with tumours.
著者:: Sewry, C, 等
出版事項: (2005)

Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury.
著者:: Mattia Quattrocelli, 等
出版事項: (2017-10-01)

Intermittent Hypoxia Inhibits Na+-H+ Exchange-Mediated Acid Extrusion Via Intracellular Na+ Accumulation in Cardiomyocytes
著者:: Huai-Ren Chang, 等
出版事項: (2018-04-01)

Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo
著者:: Lee, S-H, 等
出版事項: (2018)

Autoregulation of H+/lactate efflux prevents monocarboxylate transport (MCT) inhibitors from reducing glycolytic lactic acid production
著者:: Blaszczak, W, 等
出版事項: (2022)

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.
著者:: Li, D, 等
出版事項: (2010)

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin
著者:: Li, D, 等
出版事項: (2010)

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability
著者:: Tobias G. Schips, 等
出版事項: (2019-01-01)

Fatty acid-stimulated maturation of human IPSC-derived cardiomyocytes in engineered heart tissue
著者:: Purnama, U, 等
出版事項: (2020)

Analisis pemekaran Kabupaten Fak-fak Propinsi Papua
著者:: , SIRFEFA, Hamid, 等
出版事項: (2005)

PARCUKU: A RELIGIOUS RITUAL OF THE FAK-FAK COMMUNITY
著者:: Ade Yamin
出版事項: (2013-12-01)

Coadministration of linolenic acid and linoleic acid decreased lipotoxicity in cardiomyocytes.
著者:: Elham Zadeh Hashem, 等
出版事項: (2018-10-01)

Studi potensi perancangan PLTMH pada Sungai Kara Pinde Durik distrik Fak-fak Timur, Kab. Fak-fak Propinsi Irjabar
著者:: , KRAMANDONDO, Fransiskus, 等
出版事項: (2007)

Myocardial creatine uptake is regulated by the sarcolemmal fraction of the creatine transporter, but not by the total creatine transporter pool
著者:: Boehm, E, 等
出版事項: (2002)

Skeletal Muscle is a Source of α-Synuclein with a Sarcolemmal Non-Lipid Raft Distribution
著者:: Ibrahim Ramirez-Soto, 等
出版事項: (2022-08-01)

Uptake and metabolism of palmitate by isolated cardiac myocytes from adult rats: involvement of sarcolemmal proteins
著者:: J J Luiken, 等
出版事項: (1997-04-01)

iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction
著者:: Barnette, D, 等
出版事項: (2018)

Efektivitas organisasi Badan Pengawasan Daerah Kabupaten Fak Fak
著者:: , USWANAS, Taufiq Heru, 等
出版事項: (2004)

Sistem penghantaran faks : pelayan faks ... [et al.] / [mikrofilem]
著者:: 361231 Azmin Abdul Rahim, 等
出版事項: (1998)

Sistem penghantaran faks dari internet ke mesin faks /
著者:: 197535 Chung, Seng Kheau
出版事項: (2000)