Selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 for patients with metabolic syndrome: is the target liver, fat, or both?

Selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 for patients with metabolic syndrome: is the target liver, fat, or both?

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Stewart, P, Tomlinson, J
التنسيق:	Journal article
اللغة:	English
منشور في:	2009

مواد مشابهة

Cortisol metabolism and the role of 11beta-hydroxysteroid dehydrogenase.
حسب: Tomlinson, J, وآخرون
منشور في: (2001)

Cortisol, 11 beta-hydroxysteroid dehydrogenase type 1 and central obesity.
حسب: Stewart, P, وآخرون
منشور في: (2002)

The functional consequences of 11beta-hydroxysteroid dehydrogenase expression in adipose tissue.
حسب: Tomlinson, J, وآخرون
منشور في: (2002)

The role of 11 beta-hydroxysteroid dehydrogenase in central obesity and osteoporosis.
حسب: Tomlinson, J, وآخرون
منشور في: (2000)

Mechanisms of disease: Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome.
حسب: Tomlinson, J, وآخرون
منشور في: (2005)

A novel selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis.
حسب: Bujalska, I, وآخرون
منشور في: (2008)

11β-Hydroxysteroid dehydrogenase type 1 as a therapeutic target in the metabolic syndrome
حسب: Tomlinson, J, وآخرون
منشور في: (2005)

11beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes.
حسب: Morgan, SA, وآخرون
منشور في: (2010)

11Beta-hydroxysteroid dehydrogenase type 1 in human disease: a novel therapeutic target.
حسب: Tomlinson, J
منشور في: (2005)

Corticosteroids, 11beta-hydroxysteroid dehydrogenase isozymes and the rabbit choroid plexus.
حسب: Sinclair, A, وآخرون
منشور في: (2007)

11 beta-hydroxysteroid dehydrogenase type 1 in obese children
حسب: Wiegand, S, وآخرون
منشور في: (2007)

Type 1 11beta-hydroxysteroid dehydrogenase as universal drug target in metabolic diseases?
حسب: Oppermann, U
منشور في: (2006)

Cortisol Metabolism and Hepatic Expression of 11 beta-Hydroxysteroid Dehydrogenase Type 1 in Patients with Non Alcoholic Fatty Liver Disease.
حسب: Ahmed, A, وآخرون
منشور في: (2010)

Reduced 11beta-hydroxysteroid dehydrogenase type 1 activity in obese boys.
حسب: Wiegand, S, وآخرون
منشور في: (2007)

Cerebrospinal fluid production - A role for 11 beta-hydroxysteroid dehydrogenase type 1?
حسب: Rauz, S, وآخرون
منشور في: (2004)

The role of 11beta-hydroxysteroid dehydrogenase 1 in adipogenesis in thyroid-associated ophthalmopathy.
حسب: Tomlinson, J, وآخرون
منشور في: (2010)

Effects of glucocorticoids on fat mass and the therapeutic potential of targeting II beta-hydroxysteroid dehydrogenase type I in obesity
حسب: Tomlinson, J
منشور في: (2009)

Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity.
حسب: Tomlinson, J, وآخرون
منشور في: (2002)

11beta-Hydroxysteroid dehydrogenase type 1 regulates insulin and glucagon secretion in pancreatic islets.
حسب: Swali, A, وآخرون
منشور في: (2008)

Characterisation of 11beta-hydroxysteroid dehydrogenase 1 in human orbital adipose tissue: a comparison with subcutaneous and omental fat.
حسب: Bujalska, I, وآخرون
منشور في: (2007)

Expression profiling of 11beta-hydroxysteroid dehydrogenase type-1 and glucocorticoid-target genes in subcutaneous and omental human preadipocytes.
حسب: Bujalska, I, وآخرون
منشور في: (2006)

Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1.
حسب: Bujalska, I, وآخرون
منشور في: (2005)

11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.
حسب: Tomlinson, J, وآخرون
منشور في: (2004)

Human and rodent type 1 11beta-hydroxysteroid dehydrogenases are 7beta-hydroxycholesterol dehydrogenases involved in oxysterol metabolism.
حسب: Hult, M, وآخرون
منشور في: (2004)

Weight loss increases 11beta-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue.
حسب: Tomlinson, J, وآخرون
منشور في: (2004)

11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects.
حسب: Gathercole, L, وآخرون
منشور في: (2013)

Glucocorticoid activation by 11beta-hydroxysteroid dehydrogenase type 1: A novel pharmacological target in the metabolic syndrome
حسب: Oppermann, U, وآخرون
منشور في: (2003)

Low-dose growth hormone inhibits 11 beta-hydroxysteroid dehydrogenase type 1 but has no effect upon fat mass in patients with simple obesity.
حسب: Tomlinson, J, وآخرون
منشور في: (2003)

Liver X receptors downregulate 11beta-hydroxysteroid dehydrogenase type 1 expression and activity.
حسب: Stulnig, T, وآخرون
منشور في: (2002)

Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.
حسب: Lavery, G, وآخرون
منشور في: (2012)

11Beta-hydroxysteroid dehydrogenase type 1 in differentiating omental human preadipocytes: from de-activation to generation of cortisol.
حسب: Bujalska, I, وآخرون
منشور في: (2002)

Role of type-1 11beta-hydroxysteroid dehydrogenase in detoxification processes.
حسب: Maser, E, وآخرون
منشور في: (1997)

Active site variability of type 1 11beta-hydroxysteroid dehydrogenase revealed by selective inhibitors and cross-species comparisons.
حسب: Hult, M, وآخرون
منشور في: (2006)

Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice
حسب: Li H, وآخرون
منشور في: (2021-05-01)

Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines.
حسب: Tomlinson, J, وآخرون
منشور في: (2001)

Selective inhibition of human type 1 11beta-hydroxysteroid dehydrogenase by synthetic steroids and xenobiotics.
حسب: Hult, M, وآخرون
منشور في: (1998)

11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle.
حسب: Morgan, SA, وآخرون
منشور في: (2009)

11beta-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 diabetes mellitus.
حسب: Valsamakis, G, وآخرون
منشور في: (2004)

Function, gene organization and protein structures of 11beta-hydroxysteroid dehydrogenase isoforms.
حسب: Oppermann, U, وآخرون
منشور في: (1997)

Novel enzymological profiles of human 11beta-hydroxysteroid dehydrogenase type 1.
حسب: Hult, M, وآخرون
منشور في: (2001)