Correction of leukocyte adhesion deficiency type II with oral fucose.

We describe a simple, noninvasive, and effective therapy for leukocyte adhesion deficiency type II (LAD II), a rare inherited disorder of fucose metabolism. This disorder leads to an immunodeficiency caused by the absence of carbohydrate-based selectin ligands on the surface of neutrophils as well a...

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Détails bibliographiques
Auteurs principaux: Marquardt, T, Lühn, K, Srikrishna, G, Freeze, H, Harms, E, Vestweber, D
Format: Journal article
Langue:English
Publié: 1999