Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania.

<p>Significant selection pressure has been exerted on the genomes of human populations exposed to <em>Plasmodium falciparum</em> infection, resulting in the acquisition of mechanisms of resistance against severe malarial disease. Many host genetic factors, including sickle cell tr...

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Bibliographic Details
Main Authors: Ravenhall, M, Campino, S, Sepúlveda, N, Manjurano, A, Nadjm, B, Mtove, G, Wangai, H, Maxwell, C, Olomi, R, Reyburn, H, Drakeley, CJ, Riley, EM, Clark, TG
Format: Journal article
Language:English
Published: Public Library of Science 2018