Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

In a genome-wide association study to identify loci associated with colorectal cancer (CRC) risk, we genotyped 555,510 SNPs in 1,012 early-onset Scottish CRC cases and 1,012 controls (phase 1). In phase 2, we genotyped the 15,008 highest-ranked SNPs in 2,057 Scottish cases and 2,111 controls. We the...

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Bibliographic Details
Main Authors:	Tenesa, A, Farrington, S, Prendergast, J, Porteous, M, Walker, M, Haq, N, Barnetson, R, Theodoratou, E, Cetnarskyj, R, Cartwright, N, Semple, C, Clark, A, Reid, F, Smith, L, Kavoussanakis, K, Koessler, T, Pharoah, P, Buch, S, Schafmayer, C, Tepel, J, Schreiber, S, Völzke, H, Schmidt, C, Hampe, J, Chang-Claude, J
Format:	Journal article
Language:	English
Published:	2008

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

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