The role of the iron transporter ABCB7 in refractory anemia with ring sideroblasts

The role of the iron transporter ABCB7 in refractory anemia with ring sideroblasts

Refractory Anemia with Ring Sideroblasts (RARS) is an acquired myelodysplastic syndrome (MDS) characterized by an excess iron accumulation in the mitochondria of erythroblasts. The pathogenesis of RARS and the cause of this unusual pattern of iron deposition remain unknown. We considered that the in...

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Bibliographic Details
Main Authors: Boultwood, J, Pellagatti, A, Nikpour, M, Pushkaran, B, Fidler, C, Cattan, H, Littlewood, T, Malcovati, L, Della Porta, MG, Jädersten, M, Killick, S, Giagounidis, A, Bowen, D, Hellström-Lindberg, E, Cazzola, M, Wainscoat, J
Format: Journal article
Language:English
Published: Public Library of Science 2008

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