The interplay of supercoiling and thymine dimers in DNA

Thymine dimers are a major mutagenic photoproduct induced by UV radiation. While they have been the subject of extensive theoretical and experimental investigations, questions of how DNA supercoiling affects local defect properties, or, conversely, how the presence of such defects changes global sup...

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Autori principali: Lim, W, Randisi, F, Doye, JPK, Louis, AA
Natura: Journal article
Lingua:English
Pubblicazione: Oxford University Press 2022