The interplay of supercoiling and thymine dimers in DNA

Thymine dimers are a major mutagenic photoproduct induced by UV radiation. While they have been the subject of extensive theoretical and experimental investigations, questions of how DNA supercoiling affects local defect properties, or, conversely, how the presence of such defects changes global sup...

ver descrição completa

Detalhes bibliográficos
Principais autores: Lim, W, Randisi, F, Doye, JPK, Louis, AA
Formato: Journal article
Idioma:English
Publicado em: Oxford University Press 2022