Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis.

Tumour cells exploit both genetic and adaptive means to survive and proliferate in hypoxic microenvironments, resulting in the outgrowth of more aggressive tumour cell clones. Direct measurements of tumour oxygenation, and surrogate markers of the hypoxic response in tumours (for instance, hypoxia i...

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Bibliographic Details
Main Authors: Jubb, A, Buffa, F, Harris, A
Format: Journal article
Language:English
Published: 2010