Peri-implantation and late gestation maternal undernutrition differentially affect fetal sheep skeletal muscle development.

Poor prenatal nutrition is associated with a greater risk of adult glucose intolerance and insulin insensitivity in the offspring. Skeletal muscle is the primary tissue for glucose utilization, and insulin resistance in muscle is the earliest identifiable abnormality in the pre-diabetic patient. We...

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Bibliographic Details
Main Authors: Costello, P, Rowlerson, A, Astaman, N, Anthony, F, Sayer, A, Cooper, C, Hanson, M, Green, L
Format: Journal article
Language:English
Published: 2008