Understanding the genetic complexity of puberty timing across the allele frequency spectrum

Pubertal timing varies considerably and is associated with later health outcomes. We performed multi-ancestry genetic analyses on ~800,000 women, identifying 1,080 signals for age at menarche. Collectively, these explained 11% of trait variance in an independent sample. Women at the top and bottom 1...

Descripción completa

Detalles Bibliográficos
Autores principales: Kentistou, KA, Kaisinger, LR, Stankovic, S, Walters, RG, Lin, K, Hunter, DJ, McCarthy, MI, Millwood, IY, Pozarickij, A, Chen, Z
Formato: Journal article
Lenguaje:English
Publicado: Springer Nature 2023