Inconsistent trial assessments by the National Institute for Health and Clinical Excellence and IQWiG: standards for the performance and interpretation of subgroup analyses are needed.

OBJECTIVES: The methodology for the critical assessment of medical interventions is well established. Regulatory agencies and institutions adhere, in principle, to the same standards. This consistency, however, is not always the case in practice. STUDY DESIGN AND SETTING: Using the evaluation of th...

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Bibliographic Details
Main Authors: Hasford, J, Bramlage, P, Koch, G, Lehmacher, W, Einhäupl, K, Rothwell, P
Format: Journal article
Language:English
Published: 2010