Studies on the acetylating capacity of human colonic epithelial cells for 5-aminosalicylic acid.
Following oral administration of sulphasalazine, 5-aminosalicylic acid (5-ASA) is present in serum at very low concentrations and is mostly in the acetylated form. Analysis of rectal mucosal biopsies from patients on sulphasalazine maintenance therapy has shown that the predominant metabolite presen...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Informa Healthcare
1988
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