High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people.

The insulin-degrading enzyme is responsible for the intracellular proteolysis of insulin. Its gene IDE is located on chromosome 10, in an area with suggestive linkage to type 2 diabetes and related phenotypes. Due to the impact of genetic variants of this gene in rodents and the function of its prot...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Florez, J, Wiltshire, S, Agapakis, C, Burtt, N, de Bakker, P, Almgren, P, Bengtsson Boström, K, Tuomi, T, Gaudet, D, Daly, M, Hirschhorn, J, McCarthy, M, Altshuler, D, Groop, L
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2006