Catalytic enolate arylation with 3-bromoindoles allows the formation of β-carbolines.

Synthesis of substituted β-carbolines was accomplished by utilizing the catalytic enolate arylation reaction of ketones in conjunction with several 3-bromoindole derivatives. Quenching of the arylation reaction in situ with an electrophile allowed ready incorporation of functionality at the carbolin...

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Bibliografiske detaljer
Main Authors: Alves Esteves, C, Smith, P, Donohoe, T
Format: Journal article
Sprog:English
Udgivet: American Chemical Society 2017