Connective Tissue Growth Factor (CTGF) contributes to joint homeostasis and osteoarthritis severity by controlling the matrix sequestration and activation of latent TGFβ
<h4>Objectives</h4> <p>One mechanism by which cartilage responds to mechanical load is by releasing heparinbound growth factors from the pericellular matrix (PCM). By proteomic analysis of the PCM, we identified connective tissue growth factor (CTGF) and here investigate its funct...
| Main Authors: | , , , , , , , , , |
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| 格式: | Journal article |
| 出版: |
BMJ Publishing Group
2018
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