High Throughput Screens Yield Small Molecule Inhibitors of Leishmania CRK3:CYC6 Cyclin-Dependent Kinase
<p style="text-align:justify;">Background: Leishmania species are parasitic protozoa that have a tightly controlled cell cycle, regulated by cyclin-dependent kinases (CDKs). Cdc2-related kinase 3 (CRK3), an essential CDK in Leishmania and functional orthologue of human CDK1, can form...
| Main Authors: | , , , , , , , , , |
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| Other Authors: | |
| Format: | Journal article |
| Published: |
Public Library of Science
2011
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