High Throughput Screens Yield Small Molecule Inhibitors of Leishmania CRK3:CYC6 Cyclin-Dependent Kinase

<p style="text-align:justify;">Background: Leishmania species are parasitic protozoa that have a tightly controlled cell cycle, regulated by cyclin-dependent kinases (CDKs). Cdc2-related kinase 3 (CRK3), an essential CDK in Leishmania and functional orthologue of human CDK1, can form...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Walker, R, Thomson, G, Malone, K, Nowicki, M, Brown, E, Blake, D, Turner, N, Walkinshaw, MD, Grant, K, Mottram, J
Muut tekijät: Kita, K
Aineistotyyppi: Journal article
Julkaistu: Public Library of Science 2011