Control of artefactual variation in reported inter-sample relatedness during clinical use of a Mycobacterium tuberculosis sequencing pipeline

Contact tracing requires reliable identification of closely related bacterial isolates. When we noticed the reporting of artefactual variation between M. tuberculosis isolates during routine next generation sequencing of Mycobacterium spp, we investigated its basis in 2,018 consecutive M. tuberculos...

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Bibliographic Details
Main Authors: Wyllie, D, Sanderson, N, Myers, R, Peto, T, Robinson, E, Crook, D, Smith, E, Walker, A
Format: Journal article
Published: American Society for Microbiology 2018