Unique regulation of the active site of the serine esterase S-formylglutathione hydrolase.

S-Formylglutathione hydrolases (SFGHs) are highly conserved thioesterases present in prokaryotes and eukaryotes, and form part of the formaldehyde detoxification pathway, as well as functioning as xenobiotic-hydrolysing carboxyesterases. As defined by their sensitivity to covalent modification, SFGH...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Cummins, I, McAuley, K, Fordham-Skelton, A, Schwoerer, R, Steel, P, Davis, B, Edwards, R
Format: Journal article
Sprache:English
Veröffentlicht: 2006