Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM

The cryo-electron microscopy (cryoEM) method has enabled high-resolution structure determination of numerous biomolecules and complexes. Nevertheless, cryoEM sample preparation of challenging proteins and complexes, especially those with low abundance or with preferential orientation, remains a majo...

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Bibliographic Details
Main Authors: Ma, J, Yi, G, Ye, M, MacGregor-Chatwin, C, Sheng, Y, Lu, Y, Li, M, Li, Q, Wang, D, Gilbert, RJC, Zhang, P
Format: Journal article
Language:English
Published: Nature Research 2024