Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM

The cryo-electron microscopy (cryoEM) method has enabled high-resolution structure determination of numerous biomolecules and complexes. Nevertheless, cryoEM sample preparation of challenging proteins and complexes, especially those with low abundance or with preferential orientation, remains a majo...

Полное описание

Библиографические подробности
Главные авторы: Ma, J, Yi, G, Ye, M, MacGregor-Chatwin, C, Sheng, Y, Lu, Y, Li, M, Li, Q, Wang, D, Gilbert, RJC, Zhang, P
Формат: Journal article
Язык:English
Опубликовано: Nature Research 2024