Human lymphocytes interact directly with CD47 through a novel member of the signal regulatory protein (SIRP) family.

Two closely related proteins, signal regulatory protein alpha (SIRPalpha; SHPS-1/CD172) and SIRPbeta, have been described in humans. The existence of a third SIRP protein has been suggested by cDNA sequence only. We show that this third SIRP is a separate gene that is expressed as a protein with uni...

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Bibliografiska uppgifter
Huvudupphovsmän: Brooke, G, Holbrook, J, Brown, M, Barclay, N
Materialtyp: Journal article
Språk:English
Publicerad: 2004