Hepatitis C virus drug resistance and immune-driven adaptations: relevance to new antiviral therapy.

UNLABELLED: The efficacy of specifically targeted anti-viral therapy for hepatitis C virus (HCV) (STAT-C), including HCV protease and polymerase inhibitors, is limited by the presence of drug-specific viral resistance mutations within the targeted proteins. Genetic diversity within these viral prote...

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Detalhes bibliográficos
Principais autores: Gaudieri, S, Rauch, A, Pfafferott, K, Barnes, E, Cheng, W, McCaughan, G, Shackel, N, Jeffrey, G, Mollison, L, Baker, R, Furrer, H, Günthard, H, Freitas, E, Humphreys, I, Klenerman, P, Mallal, S, James, I, Roberts, S, Nolan, D, Lucas, M
Formato: Journal article
Idioma:English
Publicado em: 2009