Swelling of the intervertebral disc in vitro.

Slices of the intervertebral disc swell rapidly in aqueous solutions. Following swelling, a large proportion of the proteoglycans leach out. These changes can introduce artifacts into in vitro experimental work. Swelling results from the large Gibbs-Donnan osmotic pressure of the proteoglycans which...

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Bibliographic Details
Main Authors: Urban, J, Maroudas, A
Format: Journal article
Language:English
Published: Informa Healthcare 1981