Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma

Background and purpose: Tumour hypoxia is associated with a poor prognosis in head and neck squamous cell carcinoma (HNSCC), however there is no accepted method for assessing hypoxia clinically. We aimed to conduct a technical validation of a hypoxia gene expression signature using the TaqMan Low De...

Full description

Bibliographic Details
Main Authors: Betts, G, Eustace, A, Patiar, S, Valentine, H, Irlam, J, Ramachandran, A, Merve, A, Homer, J, Möller-Levet, C, Buffa, F, Hall, G, Miller, C, Harris, A, West, C
Format: Journal article
Language:English
Published: 2013