Sensitive and specific enzymatic assay for the determination of precursor forms of prostate-specific antigen after an activation step.

BACKGROUND: The proteome of the serine protease prostate-specific antigen (PSA) and its enzymatic properties have been clarified only recently. We have developed a specific and sensitive method for the measurement of active PSA and used it to measure proPSA in blood. METHODS: We used the synthetic...

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Hlavní autoři: Niemelä, P, Lövgren, J, Karp, M, Lilja, H, Pettersson, K
Médium: Journal article
Jazyk:English
Vydáno: 2002