POLE proofreading mutations elicit an anti-tumor immune response in endometrial cancer
<strong>Purpose:</strong> Recent studies have shown that 7-12% of endometrial cancers (ECs) are ultramutated due to mutation in the proofreading exonuclease domain of the DNA replicase POLE. Interestingly, these tumors have an excellent prognosis. In view of the emerging data linking mut...
| Autori principali: | , , , , , , , , , , , , , , , , |
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| Natura: | Journal article |
| Lingua: | English |
| Pubblicazione: |
American Association for Cancer Research
2015
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