Structure and mechanism of drug efflux machinery in Gram negative bacteria.

In Gram-negative bacteria, multi-component machines that span the inner and outer membranes actively extrude drugs and other toxic small compounds. Many of these machines are assembled principally from three different types of components: i) an outer membrane protein that acts as a channel and opens...

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Bibliographic Details
Main Authors: Pietras, Z, Bavro, V, Furnham, N, Pellegrini-Calace, M, Milner-White, E, Luisi, B
Format: Journal article
Language:English
Published: 2008