Structure and mechanism of drug efflux machinery in Gram negative bacteria.
In Gram-negative bacteria, multi-component machines that span the inner and outer membranes actively extrude drugs and other toxic small compounds. Many of these machines are assembled principally from three different types of components: i) an outer membrane protein that acts as a channel and opens...
Main Authors: | Pietras, Z, Bavro, V, Furnham, N, Pellegrini-Calace, M, Milner-White, E, Luisi, B |
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Format: | Journal article |
Language: | English |
Published: |
2008
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